For a population to stay in Hardy-Weinberg equilibrium, mating must be ___________________. 6.Mutation is also a violation of Hardy-Weinberg conditions, because there can be no _____________________________________________________. 7.Mutations show more quickly in a population. 8.Allelic frequency can also be altered by taxa moving in (termed ___________________) or taxa migrating out (termed ____________________). Either of these can change the composition of the __________________________, also violating Hardy-Weinberg. 9.Another violation of Hardy-Weinberg equilibrium is __________________________, because in a population at equilibrium, no alleles would be selected over any others. 10.To sum up: violations of Hardy Weinberg include a.No mutation b.No migration c.No drift d.Random mating e.No selection

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¾Next, read ‘Concept 6’ on ‘Estimating Allelic Frequency’ and answer the question posed there below: Concept 6 question: Can you count the number of recessive alleles in this population? Why or why not? ¾Next, read Concept 7 on ‘The Hardy Weinberg equation’ sample problems for Concepts 8 – 11 below. For each calculation, work the problem on your own paper, but enter your answer here. Concept 8 - Sample Problem 1: 1.) calculate q2 2.) calculate q 3.) calculatep4.) calculate 2pqConcept 9 - Sample Problem 2: How many individuals of fruit flies would you expect to be homozygous for red-colored eyes? Concept 10 - Sample Problem 3 Approximately what percent of the population are heterozygous carriers of the recessive PKU allele?

Concept 11 – Allelic Frequency vs. Genotypic Frequency What is qfor this population? Next, read ‘Design of the Experiment’ and answer questions to ‘Analysis of Results’ below 1. What are the initial pand q2. What are the final pand q3. Is the population in Hardy-Weinberg equilibrium? Explain the reason for your response. ? ? Finally, take the ‘Lab Quiz’. For each question, enter your mathematical answer (if a calculation) or explain your answer in words (if a conceptual question). 1. 2. 3. 4. 5.